Lewis & Clark's American Restaurant in St. Charles, MO. Call us at (636) 947-3334. Check out our location and hours, and latest menu with photos and reviews.

Menu for Lewis & Clark's American Restaurant in St. Charles, MO. Explore latest menu with photos and reviews.

Find your Lewis & Clark's American Restaurant in St. Charles, MO. Explore our location with directions and photos.

Large Party Reservations Lewis and Clarks is located on Main Street in the heart of Historic St. Charles. In our unique three story historic building, we have multiple options for hosting a range of events …

About Lewis & Clark's American Restaurant in St. Charles, MO. Call us at (636) 947-3334. Explore our history, photos, and latest menu with reviews and ratings.

About Lewis & Clark's American Restaurant in St. Charles, MO. Call us at (636) 947-3334. Explore our history, photos, and latest menu with reviews and ratings.

Menu for Lewis & Clark's American Restaurant in St. Charles, MO. Explore latest menu with photos and reviews.

Photo gallery for Lewis & Clark's American Restaurant in St. Charles, MO. Explore our featured photos, and latest menu with reviews and ratings.

Soup of the Day at Lewis & Clark's American Restaurant in St. Charles, MO. View photos, read reviews, and see ratings for Soup of the Day.

Gumbo at Lewis & Clark's American Restaurant in St. Charles, MO. View photos, read reviews, and see ratings for Gumbo. Different from the classic New Orleans Gumbo our version has a thicker creamy …