Background Proton pump inhibitors (PPIs) have been widely used for over 35 years. However, in recent decades, numerous ...

Objectives Probability or risk outcome estimates tailored to individual patient characteristics can facilitate more personalised care, for example, regarding treatment. Yet, the uptake of prediction ...

Objectives To evaluate the performance of large language models (LLMs) in risk of bias assessment and to examine whether prompt engineering improves their accuracy and alignment with expert reasoning.

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Objective To examine the potential errors of a general large language model (LLM) (ie, Claude 3.5 Sonnet) on data extraction from randomised controlled trials (RCTs). Design and setting An empirical ...

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3 Instituto de Investigación Sanitaria de Canarias (IISC), Tenerife, Spain 4 Fundación Instituto de Investigación Sanitaria de Canarias (FIISC), Tenerife, Spain Objectives Observing Patient ...

Seeding trials —clinical studies designed primarily for marketing rather than scientific advancement—pose underappreciated risks to research integrity and patient safety. Sukhun Kang and colleagues ...

Objectives To investigate the effectiveness and clinical relevance of kinesio taping (KT) in musculoskeletal disorders (MSDs) at different follow-ups. Design Overview of systematic reviews (SRs) and ...

14 Innovation Institute for Integration of Medicine and Engineering, West China Hospital, Sichuan University, chengdu, China Questionable research practice: a spectrum of questionable behaviours in ...