Researchers at Umeå University show that the protein METTL3 helps breast cancer cells spread. By regulating the release of ...

The core principle of mRNA vaccines is to deliver antigen-encoding mRNA into host cells via appropriate delivery vectors. Host cellular machinery is then utilized to translate and synthesize target ...

Seasonal influenza causes substantial illness and death in adults 50 years of age or older, even with current vaccines. An investigational messenger RNA (mRNA)–based vaccine called mRNA-1010 encodes ...

Someone must have been telling lies about me because when I came in for my shift this morning, I found out I was going to be fired for stealing the tip jar. “That’s what they’re saying,” Melissa told ...

A trio of common amino acids may hold the key to unlocking far more powerful gene therapies. Researchers found that adding them to lipid nanoparticles can boost mRNA delivery up to 20-fold and push ...

EDITOR’S NOTE: This story was reported in collaboration with the Global Health Reporting Center with support from the Pulitzer Center. Vita Sara Blechner’s life changed on a Saturday afternoon. The ...

Lebohang Morake, the Grammy‑winning South African composer known professionally as Lebo M, is suing a comedian for $27 million, alleging a viral joke about the opening chant of The Lion King distorted ...

Scientists are making rapid progress toward a long-awaited goal that could help to reshape cancer care: mRNA cancer vaccines with the potential to significantly boost the immune system’s ability to ...

RNA therapeutics are expanding rapidly, driving demand for manufacturing processes that can keep pace with clinical translation. Because mRNA yield and impurity profiles are jointly influenced by ...

In the cytoplasm, mRNA is regulated at both its 5’ and 3’ ends to facilitate the translation of proteins essential for the organism’s life activities 1. Erroneous or unnecessary mRNAs are degraded by ...

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...