Innovative approach expands drug discovery possibilities for targets beyond the reach of conventional methodTo be presented ...

In mouse brain cells, and in follow-up work involving worms and human cortical neurons, the team found that many axons ...

The colorful dots at the center are cytotoxic granules used to destroy infected or cancerous cells. Credit: F. Lemaitre @ ...

From the fluid mosaic model to tight junctions, cell membranes are the ultimate gatekeepers of life. They manage what comes in and out, maintain balance, and even signal to other cells. Understanding ...

A collaboration between the University of Geneva and Lausanne University Hospital has shown in new detail how the body's defenses fight back against malignant cells. Those defenses involve T ...

All lifeforms need to continuously adapt to temperature changes to survive. Now, Weill Cornell Medicine investigators ...

Researchers used cryo-expansion microscopy to map the immune synapse in near-native conditions, uncovering structural features that guide T cell targeting, granule release, and tumor cell destruction.

Just as the human body relies on organs such as the heart or liver for essential functions, cells depend on their own tiny ...

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells. Their action relies on a specialized exchange zone called the "immune synapse," ...

The body’s “killer” T cells don’t just attack—they strike with astonishing precision, forming a tiny, highly organized contact zone that lets them destroy dangerous cells without harming their ...