An experimental RNA-based therapy shows promise for ALS by preventing TDP-43 protein clumping. The therapy halted motor neuron loss in mouse models. Researchers hope to one day move the treatment to ...

I credit Jeff fully with the vigor and zest with which we lived after his diagnosis. He was a decisive man, and had built a ...

Dutch Bros' Drink One for Dane fundraiser returns May 15 to support ALS awareness and research. ALS is a progressive ...

When my father, Mickey, was diagnosed with amyotrophic lateral sclerosis (ALS), I was a sophomore in high school. Our world ...

I’ve seen how differently people respond to ALS, both those with the disease and their spouse caregivers. Those who have radical acceptance, like Todd, seem to struggle less emotionally. But it’s ...

COYA 302, an injection therapy in development for the treatment of ALS, has been awarded fast track status by the U.S. Food and Drug Administration. The therapy aims to slow ALS progression by ...

The “ Ask Me Anything ” (AMA) event was hosted on the ALS News Today Forums. Our featured guest was James Smith ...

EverythingALS has launched a new online tool called SAVA AI that uses artificial intelligence to instantly match people with amyotrophic lateral sclerosis (ALS) to clinical trials.

The ALS Association is awarding $3 million in grants to expand access to specialized care in the U.S. The new funding targets underserved, geographically isolated communities lacking multidisciplinary ...

Acurastem has received $7.5 million in funding from the California Institute for Regenerative Medicine (CIRM) to advance AS-241, its lead clinical candidate for amyotrophic lateral sclerosis (ALS) and ...

A cellular recycling system called CMA was found to be impaired in ALS motor neurons. Reduced CMA activity was linked to TDP-43 protein clumps, a hallmark of most ALS cases. Boosting CMA may be a ...

Fast-track status is intended to speed the development and review of treatments for serious conditions with unmet medical needs. It will allow Spinogenix to have more frequent interactions with the ...