Stopping tumor growth is only half the battle. Rather than killing tumor cells, many cancer therapies can only push them into ...
Figure 1. Major inducers of cellular senescence. Diverse intrinsic and extrinsic stimuli, including DNA damage, oncogene activation, telomere attrition, oxidative stress, mitochondrial impairment, ...
There exists a complex synergistic relationship among cancer, circadian rhythms, and aging: aging is a major risk factor for cancer, disruption of circadian rhythms promotes tumor initiation and ...
A new study reported that SARS-CoV-2, the virus that causes COVID, can infect dopamine neurons in the brain and trigger senescence—when a cell loses the ability to grow and divide. The researchers ...
Cellular senescence is a state characterized by permanent cell-cycle arrest, increased expression of markers such as p16^INK4a and p21^CIP1/WAF1, elevated DNA damage signals (e.g., γ-H2AX) and a ...
A new review was published in Volume 18 of Aging on May 30, 2026, titled "The love and hate relationship between cellular senescence and stemness." The review was led by first author Angelos ...
Patient populations with inflammatory musculoskeletal disorders are aging rapidly, and the research exploring aging processes ...
When the NIH Cellular Senescence Network (SenNet) published the first comprehensive Human Senescence Atlas on the cover of Cell in June 2026, it marked more than another milestone in aging research.
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