EXPORT MECHANISM: The tRNA must mature inside the nucleus before export. tRNAs are aminoacylated, and only tRNAs charged with an amino acid are exported efficiently. Export occurs when the tRNA is ...

Scientists have uncovered key new information towards understanding the crucial first step in protein synthesis, the process by which the genetic code, harbored within DNA and copied into RNA, is ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry ...

A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...