Deoxyribonucleic acid (DNA) replication is fundamental to life, yet the precise mechanics of how helicases unwind the genome for replication remain unclear. A recent study published in Nature used ...

Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and ...

A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, offering fresh insight into how human cells build and maintain chromatin, ...