Calcium (Ca²⁺) signalling is essential for cardiomyocyte function, regulating excitation–contraction coupling and excitation–transcription coupling, and contributing to mitochondrial energy production ...
Heart failure (HF) is a major global and life-threatening disease. Despite advances in therapies, the prevalence of HF is increasing owing to an ageing population and the pervasive pandemic of obesity ...
Instead, CICR acts as a dormant but dangerous silent risk factor, staying quiet under normal conditions yet becoming a major driver of pathology when RyR1 signaling is disrupted. This model resolves a ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results